Ongoing PRojects - 2025

• Contextual Interpretation of Hepatic Biomarkers in Adeno‐Associated Virus (AAV) Gene Therapy: When ALT, AST, and GGT Tell Different Stories

Status: Submitted for publication

• Optimizing Clinical Safety Through Laboratory Surveillance After AAV Gene Therapy: A Diagnostic and Management  Strategy for Anti-Capsid Immune-Mediated Toxicities

Status: In Progress 

• Pre-Existing Immunity to Adeno-Associated Virus: A Global Meta-Analysis of Anti-AAV Neutralizing Antibody Seroprevalence and Implications for Gene Therapy

Status: Preliminary results presented at 28th ASCGT Annual Meeting

Registration: CRD42025636026

• Routes of CNS Delivery for Gene Therapy: A Systematic Review and Meta-Analysis of Preclinical (non-human primate) and Clinical Studies

Status: In Progress 

• Cardiotoxicities Associated with CAR-T: A Systematic Review and Meta-analysis

Status: In Progress